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Cholinergic drugs for acid reflux

Updated: 9/7/2023

Wiki User

∙ 14y ago

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The effects of parasympathetic nervous system on the GI tract includes:

Increased motility (peristalsis)
More rapid gastric emptying
Relaxation of pyloric sphincter

Cholinergic agents used for the treatment of gastroesophageal reflux includes:

Bethanechol - this is a longer acting form of acetylcholine, acts as a general cholinergic.
Metoclopramide* - its effects are mainly seen on upper GI motility. Increases gastric emptying and increases tone of lower esophageal sphincter.

Metoclopramide* works by displaying anti-dopaminergic activity, which may not be a mechanism for decreasing emptying time of the stomach. But it appears to promote acetylcholine release or improve receptiveness of muscarinic receptors in the GI tract to acetylcholine. Metoclopramide also enhances motility of GI smooth muscle and decreases emptying time of the stomach. The side effects of metaclopramide are dopamine related CNS side effects: Extrapyramidal symptoms, anxiety, depression, drowsiness, dizziness, etc.

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Q: Cholinergic drugs for acid reflux

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What is cholinergic and anti cholinergic drugs?

Cholinergic drugs are used for urinary retention, myasthenia gravis, glaucoma. Cholinergic drugs act like the neurotransmitter ACh (acetylcholine). Anti Cholinergic (also called Cholinergic blocking) drugs block the action of the ACh. Anti Cholinergic drugs are used foe pylorospasm & peptic ulcers, bladder overactivity, parkinson's disease

What is Sar of cholinergic drugs?

The SAR (Structure-Activity Relationship) of cholinergic drugs involves a quaternary ammonium group for interaction with the receptor, an acetyl group for substrate recognition, and an appropriate spacer between these groups for optimal receptor binding. Modifications to these structural features can affect the drug's potency, selectivity, and pharmacokinetic properties.

How do you say acid reflux in french?

"acid reflux" is "reflux gastrique" in French.

Can you have kids if you have acid reflux?

Does acid reflux contribute to sterility? No. But if you have kids, their behaviour can contribute to acid reflux.

Which is not an action of cholinergic drugs?

Dilation of the pupils (Mydriasis)

What is the medical abbreviation meaning acid reflux?

GERD (gastroesophageal reflux disease) is the abbreviation meaning acid reflux.

When should cholinergic drugs be avoided?

Cholinergic drugs should be avoided when the patient has any sort of obstruction in the urinary or digestive tracts, such a a tumor, or severe inflammation which is causing blockage.

What is the purpose of cholinergic stimulants?

Cholinergic drugs are used for a variety of purposes, including the treatment of myasthenia gravis and during anesthesia.

Can acid reflux disease be transmitted?

No. Acid reflux is not contagious nor is it hereditary.

Use of vinegar for diseases?

http://www.revolutionhealth.com/drugs-treatments/rating/apple-cider-vinegar-for-acid-reflux-gerd

Can white mint aggravate acid reflux?

Mint can aggravate acid reflux, yes.

Can the duodenum be repaired and is it the cause of acid reflux?

Yes, it can be repaired and no it is not the cause of acid reflux.