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GFNHVB

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12y ago
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2mo ago

Replacing ammonia with acetic acid may affect the polarity of the solvent system, potentially leading to changes in the separation and resolution of compounds in the mixture. The Rf value could be different for codeine or other components due to the altered interaction between the solvent, compounds, and the stationary phase. This change could impact the accuracy of identification or quantification of codeine in the tablet mixture.

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Q: Codeine is presented in tablet mixtures and it has an Rf value of 0.6 what would you expect to be the effect of the Rf value of replacing the ammonia in the solvent by acetic acid?
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