Mrs. or Ms.
Salutations are gestures or greetings that are meant as an acknowledgment. The proper salutation for a current mayor is Mr. Mayor or Madam Mayor.
Mr. Mayor
Whether male or female it would be: Mayor Jane Doe or Mayor Doe (as example.)
is is correct to use Dr. Mrs. for a female doctor?
"Your Honor" or "Mr. (Mrs.) Mayor"
When addressing a female mayor and multiple council members, it is good form , regardless of gender, to address the mayor first. An example would be: The honorable (insert formal name), Mayor of(name of city) and members of the (name of city) City Council.
Mr. John Jones.
Desmond Tutu was a Bishop, so the correct salutation would be, "Your Excellency".
Dear Mr. Mayor or sometimes, such as New York, Your Honor.
the correct salutation for two men is Messrs
"Dr and Mrs Smith" is the correct salutation. (With Smith replaced with the correct surname)