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Vitamin D in high dosages can be very toxic, I hope you are talking bout 50, 000 IU.

High, infrequent dosing can lead to problems. In one recent study, blood levels rose from low to extremely high, (more than 300 nmol/l) 2 to 4 hours after a 50,000 IU oral dose, and then slowly returned to pretreatment suboptimal levels. Clearly this must disrupt normal feedback mechanisms in D and calcium regulation.

And yes, it could lead to heart problems. .

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Q: Could taking 50000 vitamin D once a week for eight weeks could this much cause heart problems?
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