Curare is a competitive inhibitor of acetylcholine. It fights with acetycholine for postsynaptic receptors.
Postsynaptic acetylcholine receptors at neuromuscular junctions
Curare acts by competitive inhibition at the nicotinic acetylcholine receptor.
Curare is not hazardous if taken by mouth; it must be administered into the bloodstream. When it is in the blood, it can cause paralysis of all nerves and muscles.
Decreased blood supply in the muscle can cause anoxia then paralysis.
cause
paralysis
an electromyogram (EMG), is used to measure the activity of muscles and to provide clues to the cause of muscle weakness or paralysis, muscle problems such as muscle twitching, numbness, tingling, or pain
Yes it is true.
It blocks the nicotinic cholinergic receptors on the muscle that normally bind the acetylcholine released by the motor neuron.
Why does oranophosphate poisoning cause muscular paralysis? Why does oranophosphate poisoning cause muscular paralysis?
Laryngoparalysis or laryngoplegia is paralysis of the larynx or voice box. Another term might be vocal cord paralysis.
Poliomyelitis can cause permanent paralysis.
Curare reduces the response to nerve stimulation because it acts as a neuro-muscular blocking agent, or muscle relaxant. It is also known as tubocurarine.
Curare is a skeletal muscle relaxant it acts as a neuromuscular blocking agent. It reduces shivering. But, can be considered quite lethal.