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What are the effects of curare given orally?
Curare is not hazardous if taken by mouth; it must be administered into the bloodstream. When it is in the blood, it can cause paralysis of all nerves and muscles.
What mechanism does curare acts by?
Curare acts by blocking the transmission of nerve impulses at the neuromuscular junction, leading to muscle paralysis. It does this by binding to and blocking nicotinic acetylcholine receptors on the post-synaptic membrane, preventing the action potential from propagating across the muscle cell membrane.
What does curare act by in the neuromuscular junction?
Curare acts by blocking nicotinic acetylcholine receptors at the neuromuscular junction, preventing the binding of acetylcholine to these receptors. This leads to muscle paralysis since acetylcholine is unable to initiate muscle contraction.
What is curare poisoning?
Curare poisoning is caused by the ingestion or injection of curare, a plant-derived toxin commonly used as a muscle relaxant. Symptoms of curare poisoning include paralysis, respiratory failure, and potentially death if left untreated. Treatment involves supporting vital functions and administering antidotes like cholinesterase inhibitors.
What is Overall effect of curare in an organism?
Curare is a plant-derived poison that blocks nicotinic acetylcholine receptors at the neuromuscular junction, leading to muscle relaxation and paralysis. This can result in impaired breathing and death if respiratory muscles are affected.
How will curare affect your brain?
Curare primarily affects the body by blocking the action of acetylcholine at neuromuscular junctions, leading to muscle paralysis. It does not directly impact the brain, as it does not cross the blood-brain barrier. However, the resulting paralysis can affect brain function indirectly by inhibiting voluntary movement and causing respiratory failure if not managed. Overall, while curare's primary effects are peripheral, the consequences can influence brain activity and consciousness.
What is The loss of sensation and voluntary muscle movements in a muscle is known as?
The loss of sensation and voluntary muscle movements in a muscle is known as paralysis. This can result from damage to the nerves supplying the muscle or due to problems within the muscle itself. Treatment and management of paralysis depend on the underlying cause.
How decreased blood supply effect muscle activity?
Decreased blood supply in the muscle can cause anoxia then paralysis.
Why does curare need animals to survive?
Curare is a plant extract that acts as a muscle relaxant and paralytic agent when it enters the bloodstream. To survive, curare needs animals to serve as hosts because it is administered as a poison to immobilize prey during hunting or as a means of defense against predators.
Which poison can make you paralyzed?
Toxins such as tetrodotoxin, found in pufferfish, and curare, used by South American tribes for hunting, can lead to paralysis by blocking nerve signals or affecting muscle function. Symptoms of paralysis can range from mild weakness to complete inability to move, and can be life-threatening if not treated promptly.
Is curare poisoning affected by the motor end plate or the axon terminal?
Curare poisoning affects the motor end plate. Curare blocks nicotinic acetylcholine receptors on muscle cells at the neuromuscular junction, preventing the binding of acetylcholine and leading to muscle paralysis.
A tear in the muscle wall through which an organ can protrude is a?
paralysis
