0
What else can I help you with?
What is Overall effect of curare in an organism?
Curare is a plant-derived poison that blocks nicotinic acetylcholine receptors at the neuromuscular junction, leading to muscle relaxation and paralysis. This can result in impaired breathing and death if respiratory muscles are affected.
What does ach do at a neuromuscular junction?
ACh (acetylcholine) binds to receptors at the NMJ (neuromuscular junction) to induce contraction of muscle.
A folded region of the sarcolemma at the neuromuscular junction?
The folded region of the sarcolemma at the neuromuscular junction is called the motor end plate. It is responsible for receiving signals from the motor neuron and initiating muscle contraction. The motor end plate is rich in acetylcholine receptors, which play a key role in neurotransmission at the neuromuscular junction.
What is the narrow space that separates the motor neuron and the skeletal muscle fiber in a neuromuscular junction called?
Neuromuscular junction or neuromuscular synapse
The synapse of a motor neuron with a muscle fiber is known as the what?
neuromuscular junction
What is another site within the neuromuscular junction that might be affected to prevent muscle contraction?
The motor endplate is the is the large, complex terminal formation by which a motor neuron axon establishes synaptic contact with a striated muscle fiber. While succinylcholine produces motor endplate depolarization at the neuromuscular junction to prevent acetylcholine release, curare and medical derivatives such as tubocurarine are non-depolarizing neuromuscular blocking agents that inhibit depolarization by blocking acetylcholine from binding to receptors on the motor endplate (i.e., the curare site of action is the nicotinic acetylcholine receptors on the postsynaptic membrane of the neuromuscular junction). Curare occupies the agonist position in competition against acetylcholine.
What is Overall effect of curare in an organism?
Curare is a plant-derived poison that blocks nicotinic acetylcholine receptors at the neuromuscular junction, leading to muscle relaxation and paralysis. This can result in impaired breathing and death if respiratory muscles are affected.
What mechanism does curare acts by?
Curare acts by blocking the transmission of nerve impulses at the neuromuscular junction, leading to muscle paralysis. It does this by binding to and blocking nicotinic acetylcholine receptors on the post-synaptic membrane, preventing the action potential from propagating across the muscle cell membrane.
Why is curare a good antidote for poisoning?
Curare is considered a good antidote for certain types of poisoning, particularly from neuromuscular blocking agents, because it can effectively reverse their effects by competing with them at the neuromuscular junction. It acts as a competitive antagonist at nicotinic acetylcholine receptors, thereby restoring normal muscle function. However, it's important to note that curare itself can cause paralysis if not used appropriately, so its application must be carefully managed in a clinical setting.
What is the most likely cause of death from curare exposure?
The most likely cause of death from curare exposure is respiratory failure due to paralysis of the diaphragm and intercostal muscles. Curare is a neuromuscular blocking agent that inhibits acetylcholine at the neuromuscular junction, leading to muscle paralysis. If respiratory muscles are affected, the individual cannot breathe, which can result in hypoxia and ultimately death if not promptly treated. Without immediate medical intervention, such as mechanical ventilation, the prognosis can be fatal.
What is the site where the muscle fiber and nerve fiber meet called?
Well of course they meet at the neuromuscular junction
curare causes paralysis?
Curare is a plant-derived toxin that acts as a neuromuscular blocker, leading to paralysis by inhibiting the transmission of nerve impulses to muscles. It specifically binds to acetylcholine receptors at the neuromuscular junction, preventing the muscle contractions necessary for movement. This paralysis can affect voluntary muscles, including those involved in breathing, which can be life-threatening without medical intervention. Historically, curare has been used by indigenous peoples in South America for hunting, applied to arrows for its paralyzing effects on prey.
What is the point of contact between a motor neuron and a skeletal muscle cell called?
This point is often called the neuromuscular junction or motor end plate. ?The neurotransmitter used here is acetylcholine.Many diseases occur with dysfunction at this junction, like Myesthenia Gravis, botulism, or Lambert Eaton Myasthenic Syndrome.
What is Curare a poison works by?
Curare is a poison that works by blocking the transmission of nerve impulses to muscles, leading to paralysis. It specifically inhibits the action of acetylcholine at the neuromuscular junction by binding to nicotinic receptors, preventing muscle contraction. This results in muscle relaxation and can be fatal if the respiratory muscles are affected, leading to asphyxiation. Historically, curare has been used by indigenous peoples for hunting, as it can immobilize prey.
How does curare cause muscle paralysis?
Curare is a competitive inhibitor of acetylcholine. It fights with acetycholine for postsynaptic receptors.
The junction between a motor neurons axon and the muscle cell membrane is called a neuromuscular junction or a?
The junction between a motor neruon's axon and the muscle cell membrane is called a neuromuscular junction or a myoneuraljunction?
What does ach do at a neuromuscular junction?
ACh (acetylcholine) binds to receptors at the NMJ (neuromuscular junction) to induce contraction of muscle.
