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CF is a genetic disorder. In order for a child to have CF, 2 recessive alleles must be present. Only two CF carriers can produce offspring with CF, only there is a 25% chance that the offspring has CF. CF carriers DO NOT have CF, but have the gene that causes it (like birds that carry West Nile).
It's a genetic disease where patients affected have both of the two copies of the gene CFTR with mutation inactivating the gene. It brings to the formation of a CFTR protein with absent or decreased function. The CFTR is a transmembrane channel that transport chlorine ions (Cl-), so the patients affected have an abnormous concentration of Cl- on the mucose leadind to an increased viscosity of mucus that causes problems expecially at the lungs and pancreas, and to the reproductive apparatus. The average life of CF patients is very decreased. The gravity of the symptoms variate from patient to patient and it depends on the kind of mutations present, so there are severe forms, mild and light forms.

cystic fibrosis is an inherited disease which means you can only get the disorder passed on to you from your parents. However because the CF allele is recessive both parents have to be carriers and even then there is a 25% chance of inheritance

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7y ago

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