Describe the process in krebs cycle?

Answer 1

The Krebs cycle, also known as the citric acid cycle, is a series of chemical reactions that occur within the mitochondria of cells. The cycle involves the breakdown of carbohydrates, fats, and proteins to produce ATP, the primary energy source for cells. The process can be divided into the following steps:

Acetyl-CoA Formation: The cycle starts with the formation of acetyl-CoA from pyruvate, which is generated during glycolysis or from fatty acids. This reaction is catalyzed by the enzyme pyruvate dehydrogenase, and results in the release of carbon dioxide (CO2) and the formation of NADH.

Citrate Formation: Acetyl-CoA then combines with oxaloacetate to form citrate, which is catalyzed by the enzyme citrate synthase. This reaction also releases CoA.

Isocitrate Formation: Citrate is then converted into isocitrate by the enzyme aconitase. This reaction involves the removal of one water molecule and the addition of another.

α-Ketoglutarate Formation: Isocitrate is then oxidized by isocitrate dehydrogenase, releasing CO2 and producing NADH. This reaction also forms α-ketoglutarate.

Succinyl-CoA Formation: α-Ketoglutarate is then converted into succinyl-CoA by the enzyme α-ketoglutarate dehydrogenase. This reaction also releases CO2 and produces NADH.

Succinate Formation: Succinyl-CoA is then converted into succinate by the enzyme succinyl-CoA synthetase. This reaction produces ATP.

Fumarate Formation: Succinate is then oxidized by succinate dehydrogenase, releasing FADH2 and producing fumarate.

Malate Formation: Fumarate is then converted into malate by the enzyme fumarase.

Oxaloacetate Formation: Malate is then oxidized by malate dehydrogenase, releasing NADH and producing oxaloacetate. The oxaloacetate can then be used to begin the cycle again.

Overall, the Krebs cycle produces 2 ATP, 6 NADH, 2 FADH2, and 4 CO2 molecules for every molecule of glucose that enters the cycle. These products are then used in the electron transport chain to produce more ATP, which can be used for cellular energy.

Answer 2

The Krebs Cycle, also known as the Citric Acid Cycle, is a series of biochemical reactions that occur in the mitochondria of eukaryotic cells. The cycle begins with the oxidation of acetyl-CoA, a two-carbon molecule, which combines with a four-carbon molecule, oxaloacetate, to form citrate. Over a series of enzymatic reactions, citrate is converted into several intermediate molecules, including alpha-ketoglutarate, succinyl-CoA, and malate, which ultimately regenerate oxaloacetate. Along the way, NAD+ and FAD are reduced to NADH and FADH2, respectively, which provide electrons for oxidative phosphorylation to generate ATP. The Krebs Cycle is an essential part of cellular respiration and provides energy for cellular processes.