yes
John Bardeen won The Nobel Prize in Physics in 1956.
John A. Pople won The Nobel Prize in Chemistry in 1998.
John F. Kennedy was never awarded the Nobel Peace Prize.
John Howard Northrop won The Nobel Prize in Chemistry in 1946.
John Raleigh Mott won The Nobel Peace Prize in 1946.
Saint-John Perse won The Nobel Prize in Literature in 1960.
Albert John Lutuli won The Nobel Peace Prize in 1960.
John Cowdery Kendrew won The Nobel Prize in Chemistry in 1962.
John Robert Schrieffer won The Nobel Prize in Physics in 1972.
John C. Polanyi won The Nobel Prize in Chemistry in 1986.
John E. Walker won The Nobel Prize in Chemistry in 1997.
John B. Fenn won The Nobel Prize in Chemistry in 2002.