He had murders go kill them both
Lady Macduff has one son in Shakespeare's play Macbeth.
Well, if you mean killed, there were many! King Duncan, Banquo, Lady Macduff, Lady Macduff's son, other members of the Macduff family and Macbeth!
Lady Macduff and her son were killed by Macbeth's murderers. He killed them because he was really afraid of everything (after witches' predictions) and wanted to harm Macduff.
Malcolm (Duncan's son) did not kill Macbeth, it was Macduff (Thane of Fife).
The assassins in Macbeth kill Banquo, a close friend of Macbeth, and attempt to kill Fleance, Banquo's son. They are hired by Macbeth to eliminate any potential threats to his throne, as Banquo's descendants are prophesied to inherit the kingdom.
Lady Macbeth pushes Macbeth to kill Duncan in act 1. She is stronger and more manly than Macbeth.
Macbeth, Lady Macbeth, Banquo, Fleance, Duncan, Malcolm, Donalbain, Macduff, Lady Macduff, their son, Lennox, Ross, Siward, Young Siward, the Porter, the Doctor, the Waiting Woman, and a number of messengers.
Macbeth gives orders to kill his whole family. They killed his wife, son, and servants. Anyone who were in Macduff's castle
The Macbeth family victim list is: King Duncan, his two chamberlains, Banquo, a fellow general, but his son escapes, Lady Macduff and her children (Lady Macduff's murder is not shown onstage to emphasize the horror of killing children) Macbeth also kills young Siward towards the end
Macbeth didn't think Macduff was a threat because the witches said "None of woman born shall harm Macbeth." Macbeth welcomes this good news and, assuming Macduff was born the natural way, Macbeth thinks he has nothing to fear.
Because macduff harbors suspicions about the person who actually murderd King Duncan, therefore he turnes against Macbeth and consequently was absent from his coronation. Macbeth organises to kill her for revenge and also to set a distraction to protect himself from an enraged Macduff.
The Macbeth family victim list is: King Duncan, his two chamberlains, Macbeth's fellow general Banquo, Lady Macduff and her children. Eventually Lady Macbeth kills herself. Macbeth also kills young Siward towards the end and McDonald along with young siward during the battle when the forest "walks" up to the castle. the above is not exactly true - Macbeth kills - the traitorous Macdonwald, (mentioned in 1.2). Duncan, his two sleeping chamberlains, and young Siward. That's it. He hires murderers to kill Banquo and Fleance (they only get Banquo), as well as to kill Macduff and his family (they only get her son, and presumably, Lady Macduff - but in the text she exits before being killed) There is no evidence that Lady Macbeth kills herself, other than a line that she "tis thought, by self and violent hands took off her life"