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1) nicotinic acetyle choline receptors are ligand gated ion channels, where as mucarinic Ach receptors are G-proteins coupled receptors system.
2) nicotine is a agonist/ muscarine( a toxin produced by certain mushrooms) is a agonist.
3) action of nicotine is fast(1-2msec)/action of muscarinic is slow (100-250msec).
4) in case of nicotinic ach receptor, subtypes based on different subunit composition.muscle and neuronal classification/in case of muscarinic receptor at least 5 receptors subtype have been described by molecular cloning.
5) in case of nicotinic receptor agonist effects blocked by tubocuranine/in case of muscarinic receptor agonist effects blocked by atropine.
6) nicotinic receptor found at neuro muscular junction of skeletal muscle, on the post ganglion neurons of the parasympathetic nervous system and on many neurons on the brain(hypothalamus)/muscarinc receptor found at neuromuscular junction of cardiac and smooth muscle as well as on glands and on the post ganglionic neurons of the sympathetic nervous system.
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∙ 12y ago
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What neurotransmitter is found at the synapse between nerves and human skeletal muscle cells?
Acetylcholine is the neurotransmitter at the neuromuscular junction.
Why does atropine effect histamine receptors?
It doesn't atropine only acts on muscarinic receptors (it's a competitive antagonist here for ACh), but histamine acts on different receptors (histamine receptors). There is no direct interaction between atropine and histamine receptors
What is difference between enzyme and receptor?
Enzyems are highly selective catalysts. Receptors are not very highly selective catalysts.
What is the difference between an excitatory synapse and an inhibitory synapse?
Synapses are junctions that allow a neuron to electrically or chemically transmit a signal to another cell. Synapses can either be excitatory or inhibitory. Inhibitory synapses decrease the likelihood of the firing action potential of a cell while excitatory synapses increase its likelihood. Excitatory synapses cause a positive action potential in neurons and cells. For example, in the neurotransmitter Acetylcholine (Ach), its binding to receptors opens up sodium channels and allows an influx of Na+ ions and reduces membrane potential which is referred to as Excitatory Postsynaptic potential(EPSP). An action potential is generated when the polarization of the postsynaptic membrane reaches threshold. ACh acts on nicotinic receptors which can be found at the neuromuscular junction of skeletal muscles, the parasympathetic nervous system, and the brain. It also acts on muscarinic receptors found at neuromuscular junctions of the smooth muscles, glands, and the sympathetic nervous system. Inhibitory synapses, on the other hand, cause the neurotransmitters in the postsynaptic membrane to depolarize. An example is the neurotransmitter Gamma Aminobutyric Acid (GABA). The binding of GABA to receptors increases the flow of chloride (CI-) ions in the postsynaptic cells raising its membrane potential and inhibiting it. The binding of GABA to receptors activates a second messenger opening potassium channels.
What is the relationship between olfactory and gustatory receptors?
Gustatory receptors are part of the sense of taste. They are in your mouth. Olfactory receptors are part of the sense of smell. They are in your nose.
What are the connections between the receptors in the skin and the CNS?
not a clue
What is the connection between the receptors in the skin and the CNS?
i duunno
What the similarities between enzymes and receptors?
They both have ligands.
What the difference between Analog and Agonist?
An agonist causes action while an analog just mimics another chemical compound. Agonist bind to and activate receptors and cause a biological response.
What is the difference between feel and sense?
There are many sense organs in the body like touch receptors, pressure receptors, heart receptors, taste receptors, sound receptors, etc. All these receptors when stimulated result in changes in tone or isometric contraction of skeletal muscles around them or in the entire body.Sensation:Sensation is the observation of change in tone of skeletal muscles induced by a single sense organ.Thus, heat, sound, etc are sensations.Feeling:Feeling is the observation of changes in tone of skeletal muscles induced by many sense organs or continuous changes in a single sense organ.Thus, coffee induces a feeling and so does a song.
What is the difference between protein hormones and steroid hormones and how they communicate with their target cells?
Steroid hormones arelipid-soluble and can dissolve easily into the cell membrane of the target cell to connect with receptors. Protein hormones are water-soluble and connect with receptors at the membrane because it can't diffuse through the membrane.
What do peripheral nervous system sensory receptors do?
Sensory receptors provide the connection between the stimulus such as heat, cold, and pain and the CNS.
