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Yes, its called evergreening, they change or patent parts iof the manufacturing process or procedure. Sometime even changing the molecule slightly wll extend the patent. Yes, the most common practices include: - changing the salt or physical form, as micro/macrocrystals - changing the dissolution rate, as sustained-release formulations - changing the strengths to allow for more dosing combinations - making the original drug into a combo product, usually with another of their meds - changing the racemic form to a mirror-image isomer - applying to the FDA for new indications for the drug - selling exclusive rights to a generic manufacturer - selling a generic version of their own brand name drug themselves

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15y ago
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Q: Do drug companies devise ploys to thwart patented drugs from going generic after the 20 year patent expires?
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