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They can if you eat too many in one sitting.
Grapes contain natural sugars, called fructose. Fructose causes gas when it reacts with acids in your stomach. Gas in your digestive system can cause diarrhoea.
A lot of foods cause gas though - green beans, brussels and so on.
As long as you eat a balanced diet and don't shovel in grapes like popcorn, you'll be fine.
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