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No, there is no proof of that. It is thought that vaccines are good for the function of the immune system because they give it "exercise"; or at least they are not bad for the immune system. Some believe that if the immune system isn't triggered to respond to an antigen periodically, it will not function as well when a real antigen invades the body, in sort of a "use it or lose it" way. That may not actually happen in the immune system, but many body systems and parts do work that way.

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