Do you ever lose the weight gained from taking Zoloft after stopping the drug?

Weight is a phenomenon that has been blamed on many things, but the simple reality is, it's all a matter of diet and exercise. The Zoloft may have given you a better appetite. Many people tend to be unable to eat when depressed. While a side effect of Zoloft is slight weight gain, that may most simply be attributed to an increased appetite. Prozac tends to help people loose weight. Maybe that works well for people who tend to overeat when they're depressed. In any case, you'll need to change your diet/exercise habits if you want to loose the weight.