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Short answer: Kind of

Longer but more useful answer: Hanging upside down can help more oxygen and blood flow to your brain, therefore making your brain work more efficiently and quickly for a certain amount of time. It can make your brain feel more active and not sluggish. However, if you hang upside down for a very long time (let's say hours) too much pressure and blood will get congested in your brain, which may lead to seizures. Hanging upside down for a short time may still give you an eye migraine or a normal headache because your eyes have pressure buildup and they get strained very quickly.

Moral of the story:

Don't hang upside down for hours. Stick to a couple of minutes.

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