Yes it does
Iran, Cuba, and N. Korea
The two countries do not really have relations. Under the Obama presidency, some ties have been restored between the US and Cuba, but the two countries continue to view each other with suspicion and distrust.
The US promtly ended diplomatic relations and created an embargo against Cuba that still stands today.
The phrase no man is an island means that human beings do not thrive when isolated from others. When applied to Cuba it can be shown that when they are isolated they do not thrive as much as when they have contact with other countries. Cuba has never been stronger than when it had ties to the Soviet Union. The US does not have formal diplomatic relations with Cuba, and the offer to purchase Cuba from the Spanish Empire has waned. It has intention to maintain an embargo until the reintroduction of capitalism in Cuba. But exports from the US to Cuba in the industries of foods and medical products are permitted. In January 2011, the Obama administration eased specific travel and other restrictions between Cuba and the US.
Guantanamo Bay
The US had little involvement in Cuba under Cleveland. I am not aware that he had made any public statements about Cuba. He opposed US interference in the internal affairs of Hawaii.
Fidel Castro planned to create a communist government in Cuba, and it seemed dangerous having a country with communist ties that close to the continental US. This was soon proved true in the Cuban Missile Crisis of October, 1962.
Little Havana in Miami.
The United States and Cuba became closely linked economically through trade and investment, particularly during the early 20th century. The US invested heavily in Cuban industries, such as sugar and tobacco, and became a major trading partner. However, this relationship changed drastically after the Cuban Revolution in 1959, leading to economic sanctions and strained bilateral ties.
Events in Cuba were the excuse for the United States to declare war on Spain. In doing so the US explicitly denied any territorial ambitions in Cuba. As a result it was not politically possible for the US to take Cuba as a possession. Instead the US controlled Cuba for a few years and then reorganized it as a sovereign nation.
There are no herbs imported to the US from Cuba. The US does not trade with Cuba.
There is a trade embargo with Cuba, the US does not trade anything with Cuba.