Isis and Osiris are brother and sister.
She is sister-wife of Osiris. Seth is also her brother. Nephthys is the sister-wife of Seth, and the sister of Isis.
Nephthys
Isis and Nephthys.
Nephysths
Isis is the daughter of Nut and Geb, the sister and wife of Osiris and the mother of Horus.
Isis had three brothers, Osiris, Horus (the elder), and Seth. She also had a sister named Nephthys. Isis eventually married her brother Osiris.
For Egyptian gods and goddesses, at least Osiris, Isis, Horus, Set, and Nepthys, it is sort of like reincarnation but not. So, originally Osiris, Isis, Horus, Set, and Nepthys were all brother and sister but then later on the story was told differently with Osiris and Set still being brothers and Osiris being married to Isis and Horus being their son while Set and Nepthys were married.
Isis,mother of Horus the Avenger.
Horus was the son of Osiris and Isis. But in some other stories these three are depicted as brothers and sister.
Osirus was married to Isis. Isis is also the sister of Osirus. Horus is the son of Isis and Osirus. Set is the enemy and brother of Osirus. Anubis is his son and god of the dead.
Osiris and Isis were husband and wife, but also sister and brother.This may sound odd, but incest was very commen in ancient civilisations. Isis and Osiris had a son together, called Horus.