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It shouldn't stop working, no. Have you been going to your regular therapy so you can learn how to deal with stress and your depression? That's the only sure cure because if you're not doing therapy, your depression is going to get worse over the years. Lexapro is a good antidepressant because it has few side effects and doesn't make you drowsy like some of them do. If you're working on the therapy end regularly, and still having depression, ask your psychiatrist about adding a second drug (like Abilify) or trying some non-medication treatments like sunlight bulbs for seasonal depression.

Another thing that works with many people is to get out of the house and do something for someone else - volunteer at your local shelter or hospital, or join Habitat for Humanity or another charitable organization.

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8y ago
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14y ago

I have been on 20 mg for about 10 years, and im still happy as a clam . ;-) I think once you play around with dosing and find your "Happy Place" you should have sucess.

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Q: Does Lexapro loose effectivness over time?
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They can be combined with no known interactions. Nevertheless, it is advised that if you need to take paracetemol on a long term basis that you speak with a doctor. Lexapro and Paracetemol are both heavily processed by the liver. While Lexapro is not known to cause liver damage, Paracetemol has been known to cause liver damage over time.


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