Short answer, yes. I can't say more without giving away spoilers.
The Mark of Athena is mainly centered around Annabeth.
First chapterof Mark of Athena
First chapterof Mark of Athena
Annabeth has to rescue Nico
I don't know who will narrate the Mark of Athena except for Annabeth, but I'm hoping that Percy, Jason, and Piper also narrate along with Annabeth.
In chapter 1; Annabeth. Annabeth, Percy, Leo, and Piper.
annabeth, leo, piper, and percy
Athena never had a husband, Annabeth was born from Athena's head...
The answer will not be known until October 2012. There is a high chance though as Annabeth and Percy are dating.
I will not reveal too much about it for people who have not yet read this, but the 7 heroes of olympus meet each other in camp jupiter and hey go on a quest to find - and close - the doors of death. However, Annabeth has a secret - a command from her mother. 'Follow the Mark of Athena. Avenge me.' Annabeth will meet the enemy of Athena, who has killed children of Athena for centuries. Nico is missing after trying to find the doors of death and in Mark of Athena, you will find out what happened to him and you will also see that co-operation between Camp Half-Blood and Camp Jupiter may be very hard.
Personally, I like the reunion of Percy and Annabeth, or maybe when Annabeth was fighting Arachne.
There are four actually and they are Percy, Annabeth, Piper, and Leo.