No.
Gentamicin is an aminoglycosidic sugar which is Highly water soluble . It is
widely distributed in extracellular fluid and does not penetrate ocular tissue, nor readily crosses the blood-brain barrier. However The drug tends to accumulate in the kidneys, and the inner ear, explaining the reason for nephro and ototoxicity.
Aminoglycosides are able to cross the placental barrier, and may cause nerve or nephrotoxic effects to the fetus.
no, the penicillins do not cross blood brain barrier.
YES
meropenem
It means that in order to cross a barrier, for example a cell membrane, a substance must have a facilitator substance to make it permeable to the barrier. For instance, glucose cannot enter cells unless insulin is present to facilitate the diffusion of glucose from blood to cell. Without the insulin, or with damaged insulin receptors on the cell membrane, the cell membrane remains impermeable to glucose and it cannot enter the cells, so it remains in the blood plasma. This is what causes diabetes.
Neurons cross from the right side to the left, as do neurons cross from the left to the right, meaning your right side of your brain controls your left, and your left controls your right side.
The brain is (in effect) cross-wired; the left side of the brain controls the right side of the body, and the right side of the brain controls the left side of the body. The heart is controlled by the brain stem witch is mid-line and at the bottom.
Axons from each retina cross at the optic chiasm.
Meningitis, by definition, is an inflammatory process of the meninges, which constitute the blood brain barrier (BBB). Inflammation makes the blood brain barrier more permeable to chemicals, such as antibiotics. Under normal circumstances, penicillin does not cross the BBB very well, but when inflamed, it can cross more readily.
Netilmicin does not cross the blood-brain barrier.
Insulin does crosses the blood brain barrier. Insulin crosses the blood brain barrier through the process of receptor-mediated transcytosis.
Yes. Valium (diazepam) does indeed cross the blood brain barrier. It is one of the more lipophilic of the benzodiazepine medications.
Acetohexamide crosses the blood-brain barrier, which is why it is not prescribed to patients who might show sensitivity to this action.
meropenem
It is water soluble...
Yes
The blood barrier is located in the brain. It is known as the blood brain barrier and is located in the middle of the ventricular system. It keeps many substances from being able to cross into the brain.
Meningitis, by definition, is an inflammatory process of the meninges, which constitute the blood brain barrier (BBB). Inflammation makes the blood brain barrier more permeable to chemicals, such as antibiotics. Under normal circumstances, penicillin does not cross the BBB very well, but when inflamed, it can cross more readily.
Inducing TNF
Antidepressants, alcohol, cocaine