No. Muscarinic receptors are affected by acetylcholinergic neurotransmitters (ie. muscarine, atropine). Only the parasympathetic nervous system have muscarinic receptors.
Epinephrine affects adrenergic receptors (symapthetic nervous system).
Acetylcholine.
Depending on the effector organ it can be inhibitory or excitatory. The muscarinic receptors are activated from the parasympathetic nervous system. So the effect of muscarinic receptors activated on the heart, it will slow the heart down. However, on the gastrointestinal tract, it will increase motility.
Agonist is muscarine and antagonist is atropine.
Atropine antagonises central muscarinic receptors (remember, the parasympathetic nervous system is made up of muscarinic and nicotinic receptors). This muscarinic receptor antagonising alters temperature regulation in the hypothalamus -- the mechanism how it works is unfortunately not understood. But is is known that it reduces blood flow to the skin, thus reducing the ability for the body to lose heat and increasing body temperature. Similar to Adrenaline (Epinephrine for you North American types) I take it, although a brief search could not link adrenaline to hyperthermia (if you know of anything, please let me know).
Nicotinic receptors are closed until ACh molecules bind to the receptor proteins.
The two types of receptors that bind acetylcholine are nicotinic receptors and muscarinic receptors. Nicotinic receptors are ionotropic receptors found at the neuromuscular junction and in the autonomic ganglia, while muscarinic receptors are G-protein coupled receptors found in various organs like the heart, lungs, and digestive system.
Atropine does not only block nicotinic receptors but also acetylcholine at muscarinic receptors
Muscarinic receptors
Atropine
Acetylcholine.
Depending on the effector organ it can be inhibitory or excitatory. The muscarinic receptors are activated from the parasympathetic nervous system. So the effect of muscarinic receptors activated on the heart, it will slow the heart down. However, on the gastrointestinal tract, it will increase motility.
nicotinic and muscarinic
muscarinic receptors
The muscarinic receptors in the vasculature are not inneravated by the parasympathetic nervous system. Therefore, atropine binds to these receptors, but causes no response since it is a pure muscarinic antagonist.
Organs innervated by the parasympathetic nervous system. One addition to that are sweat glands. They are innervated by sympathetic nervous system, however, they have muscarinic receptors, NOT adrenergic receptors.
Epinephrine or more commonly known as adrenaline bind to adrenergic receptors. These adrenergic receptors are a type of G-protein coupled receptors
Agonist is muscarine and antagonist is atropine.