yes
yes
You can cross the US by river only if you are going north to south (south to north is harder) but not if you are going east to west, or west to east.
east to west Interstates with odd numbers go north to south Interstates with even numbers go east to west
145 km or so taking this route:Take HIGHWAY 410 - SOUTH, from Brampton, to HIGHWAY 401 - EAST to TORONTO (or to HIGHWAY 407 ETR (Express Toll Route) - EAST).Take HIGHWAY 401 - EAST (or HIGHWAY 407 ETR - EAST) to HIGHWAY 400 - NORTH to BARRIE (at EXIT 66 off HIGHWAY 407 ETR).Take HIGHWAY 400 - NORTH to HIGHWAY 11 - NORTH to ORILLIA at EXIT 105, near Barrie.Take HIGHWAY 11 - NORTH to Orillia.
The major north/south highway in Grand Forks, North Dakota is I-29/US81. The main east/west highway in Grand Forks is US2.
562 km taking this route:Take HIGHWAY 9 EAST from Arthur to HIGHWAY 400. Follow signs to HIGHWAY 400 SOUTH to TORONTO.Take HIGHWAY 400 SOUTH to HIGHWAY 401 EAST at EXIT 21 in TORONTO. Make sure you get onto the EXPRESS LANES.Take HIGHWAY 401 EAST across to HIGHWAY 416 NORTH to OTTAWA at EXIT 721A.Take HIGHWAY 416 NORTH to Ottawa. To get to the city proper, take HIGHWAY 417 EAST.
EAST or WEST or SOUTH or NORTH?
242 miles (390 kilometres) taking this route:Take HIGHWAY 6 SOUTH from Regina to HIGHWAY 39 EAST to WEYBURN.Continue on HIGHWAY 39 to the U.S.A. border x-ing at NORTH PORTAL (SESKATCHEWAN, CANADA) and PORTAL (NORTH DAKOTA, U.S.A.).Cross the border into U.S.A. Continue on U.S. 52 SOUTH from the Portal to Minot.
Interstate 77 crosses West Virginia from north to south. It crosses the Ohio River near Parkersburg and goes south through Charleston (state capital) and into Virginia.
70 kilometres taking this route:Take HIGHWAY 400 SOUTH to HIGHWAY 401 at EXIT 17 in North York, TORONTO.Follow signs to HIGHWAY 401 EAST; take HIGHWAY 401 EAST to Whitby.
The major highways in the state of Iowa are Interstate 35 and Interstate 29. They join the north and south part of the state. Interstate 80 and Interstate 380 join the east and west side of the state.
74 kilometres taking this route:Take HIGHWAY 410 SOUTH from Brampton to HIGHWAY 401. Follow signs to HIGHWAY 401 EAST to TORONTO.Take HIGHWAY 401 EAST to HIGHWAY 400 NORTH to BARRIE at EXIT 359.Take HIGHWAY 400 NORTH to SIMCOE RD. 88 - EAST to BRADFORD at EXIT 64A.Take SIMCOE RD. 88 - EAST (Holland St) to Bradford.