Quite significantly as that body part is no longer there.
Every part of the body is vulnerable
Lung
eyes
Eye
the head
A loin is a part of the body and a particular cut of meat. As a body part the chest is bigger than the loin, as cut of meat a side of beef is bigger than a loin of beef.
Bones
Tongue
Depressants slow (or depress) the functioning of the entire body.
It affects the kidney.
hair and nails
eyes