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This question is somewhat ambiguous and rather broad but I will do my best to answer completely. The two main types of effects for drugs on the CNS (Central Nervous System) is to depress it, or slow it down; or to stimulate it, or speed it up. Depressing the CNS lowers blood pressure, slows breathing and heart rate and if too severe can stop both. These will also cause drowsiness, memory loss, cognition, motivation, and possibly death. Stimulating the CNS will cause a rapid heart rate, raised blood pressure and can also affect breathing. Side effects of this are anxiety, restlessness, sleeplessness, hyperactivity, and in severe cases/overdoses can cause stroke and/or heart attack. Some drugs do not belong in either category but still affect the CNS. These drugs are prescription medications and would have to be considered individually.
CNS
amphetamine and CNS stimulating drugs
CNS (central nervous system) stimulant schedule II federal classification
Prolactin is a hormone and any drug which acts on the CNS can affect hormone levels - either by intent, or as an unintended side effect. CNS stimulants often increase dopanine levels .. and dopamine inhibits the secretion of prolactin (which controls lactation).
benzodiazedines
Complete understanding of drugs Pharmacokinetics Pharmacodynamics Action of drugs on different system i.e; GIT, CNS, CVS, ANS, Etc
the endothelium of CNS capillaries forms a blood-brain barrier
They all alter the functioning of the CNS (central nervous system).
Depressants. aka things such as alcohol, heroine, & many other drugs.
it is very dangerous to take them together ,both are CNS depressant.