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Yes, obesity is a significant risk factor for endometrial cancer. Women who are obese have a higher risk of developing endometrial cancer compared to those with a healthy weight. This increased risk is believed to be due to several factors:

Hormonal Imbalance: Obesity is associated with higher levels of estrogen, which can stimulate the growth of the endometrium (the lining of the uterus), potentially leading to cancerous changes.

Insulin Resistance: Obesity often coexists with insulin resistance, which can lead to higher levels of insulin and insulin-like growth factors. These factors may promote the development of endometrial cancer cells.

Chronic Inflammation: Obesity is linked to chronic inflammation, which can contribute to cancer development and progression.

Adipokines: Fat cells produce hormones and signaling molecules called adipokines, which can affect cell growth and inflammation, potentially influencing cancer risk.

Maintaining a healthy weight through diet and exercise is one of the strategies recommended for reducing the risk of endometrial cancer, especially for women with other risk factors such as hormonal imbalances or a family history of the disease.

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raghu.punarjan

Lvl 8
1y ago

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