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Sweating shouldn't really change it, no. There are many types of patches now, but some are indeed stimulated by heat so the increased body temperature that sweat is a reaction to may cause a patch to release more fentanyl at a time. The way these patches work are quite complex, though, and once it's in your body who knows what happens to get it working?

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Q: Does sweating increase the amount of Fentanyl released in a patch?
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