Double-Dummy A technique for retaining the blind when administering supplies in a clinical trial, when the two treatments cannot be made identical. Supplies are prepared for Treatment A (active and indistinguishable placebo) and for Treatment B (active and indistinguishable placebo). Subjects then take two sets of treatment; either A (active) and B (placebo), or A (placebo) and B (active). Difficulties in achieving the double-blind ideal can arise: the treatments may be of a completely different nature, for example, surgery and drug therapy; two drugs may have different formulations and, although they could be made indistinguishable by the use of capsules, changing the formulation might also change the pharmacokinetic and/or pharmacodynamic properties and hence require that bioequivalence of the formulations be established; the daily pattern of administration of two treatments may differ. One way of achieving double-blind conditions under these circumstances is to use a 'double-dummy' technique. This technique may sometimes force an administration scheme that is sufficiently unusual to influence adversely the motivation and compliance of the subjects. Ethical difficulties may also interfere with its use when, for example, it entails dummy operative procedures. Nevertheless, extensive efforts should be made to overcome these difficulties.
The best biometric design for a clinical trial is a double-blind trial comparing the drug against another drug, or placebo. This means that neither the doctor nor patient can tell which treatment the patient is on. To do this both treatments must look identical. Sometimes this is not possible, perhaps 1 drug is a pill, and one is a liquid. In this case biometrics dictates that a double blind double dummy design is used. A dummy liquid is made up to look like the active liquid, and a dummy pill is made up to look like the active pill. Patients then are given either the active pill and the dummy liquid, or the active liquid and the dummy pill.
A double dummy study is a technique in administering supplies in a clinical trial. It refers to a method of blinding wherein the placebo is administered to both treatment groups.
During the clinical trial, all patients are given both placebo and active doses in alternating periods of time.
During the clinical trial, all patients are given both placebo and active doses in alternating periods of time.
During the clinical trial, all patients are given both placebo and active doses in alternating periods of time.
A dummy door knob is used on doors that need to look the same but do not need a functional lock. Double closet doors, sometimes one half of a double door.
swimming humming yummy dummy shammed whammy
If treatments are classed as A, B and C, and say, for example, C is placebo, then during the trial, every patient will receive A at some point, B at some other point and also C at another time. Therefore each patient is 'dummy' to what they are receiving. It's a 'triple' dummy because there are 3 different treatments.
no dummy no dummy no dummy
A dummy is called a dummy for two reasons one because he is dumand not smart and does not know things second is because he is a dummy.
The dummy in the window had a missing arm.She put the dummy in the baby's mouthHe is such a dummy.
a dummy