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A series of solvents with an increasing degree of polarity, generally used to explain solvent strength in liquid-solid or adsorption chromatography. A nonpolar solvent such as pentane would be at one end of the scale; dichloromethane would be an intermediate solvent; a strongly polar solvent, such as water, would be at the other end of the scale. Thus, when developing a method or running a gradient, an eluotropic series is useful for selecting solvents.

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6mo ago

The eluotropic series in chromatography refers to a list of solvents ranked based on their ability to elute (separate) components of a mixture from the stationary phase. Solvents higher in the eluotropic series are more polar and have stronger interactions with the stationary phase, thus making it easier for components to move through the column. The eluotropic series is useful in selecting appropriate solvents for different chromatographic separations.

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Q: Eluotropic series mean in relation to chromatography?
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