Your question is too broad to give a definitive answer, especially given the huge number of Opera companies. However, Marian Anderson was the first African-American sing for the Metropolitan Opera [1955] and also the first to be named a permanent member of Metropolitan Opera Company. Such a delay was purely based on racial discrimination.
Bert Williams was one of the first African American to perform in theatre with Florenz Ziegfeld
She was the first African-American to perform at the Mocambo
The first African American record company was Black Swan Records. It was started in 1921 by Harry Pace in Harlem, New York.
William Harvey Carney was the first African American to perform an action for which a Medal of Honor was awarded, but Robert Blake was the first African American to actually receive the Medal.
Marian Anderson
Daniel Hale Williams
Carnegie Hall is one of the most famous concert venues in Manhattan, New York. In 1892 Sissieretta Jones became the first African-American to perform there.
Levi Jackson was the first African-American football captain at Yale University, and the first African-American executive at Ford Motor Company.
Marian Anderson
Marian was the first African American to perform for Franklin D. Roosevelt and his wife Eleanor Roosevelt.
The first African-American girl to play soccer is Briana Scurry.
The first African American superhero was falcon