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HOW TO Enumerate and describe/define the other USP/NF official methods of moisture determination.?
BS PHARMACY STUDENT
USP offers two method of determining moisture content:
The karl fischer titration is a moisture determination method specific for water and is suitable for samples with high mositure content (titrimetry) and also for those with water contents in ppm range (coulometry). it was originally developed for non aqeuous liquids, but is also suitable for solids if these are soluble or if the water they contain can be remove by heating in a stream of gas or by extraction.
Gravimetric method the process by which the drug is dried at 105℃
Until a constant weight, so it is considered a destructive method for plant material
BS PHARMACY STUDENT
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