Essentially a lot of the pathways affected in AD are run by AceylCholine so a central ACHE inhibitor would allow increased ACH in the CNS and bypass the damage that may be inhibiting the synaptic transmission. This is all theoretical of course.
Kevin
Bronchiolitis
EPM is detected through physical exam, blood testing and cerebrospinal fluid testing. It is important to note that a positive blood test may simply indicate exposure to the parasite and not disesae, therefore a diagnosis should not be made based upon a blood test alone.
You most probably would not be able to live for very long should your mitochondria stop working. You would quickly have a deficit in energy-carrier molecules ATP and so life-sustaining metabolism would come to a halt.
noninfectious diseases dont "spread" as they are "caused by either the environment, nutritional deficiencies, lifestyle choices, or genetic inheritances. Unlike infectious diseases, non-infectious diseases cannot be spread from person to person, although some kinds can be passed down genetically to the children of a carrier."
Diseases caused by pathogens are often contagious and include things such as Meningitis, Influenza and Tuberculosis. Diseases not caused by pathogens are generally things which go wrong in the body. For example, Cancer, Multiple Sclerosis and Motor Neurone Disease are all diseases not caused by pathogens.
If they have it or suspect they have it, they are probably fearful of the potential fate headed their way. They fail to realize, however, that by educating themselves on what they might or does, or someone else they care for may or does, in fact have, theyl can prevent or at least slow down the progression of the disease to AIDS. Yes, you read that right! HIV doesn't have to progress to AIDS! But WITH PROPER TREATMENT... which usually consists of 25-30 pills a day...
DefinitionDiabetes is a chronic (lifelong) disease marked by high levels of sugar in the blood. Those with diabetes are at high risk for a number of complications.See also:DiabetesGestational diabetesMetabolic syndromeType 1 diabetesType 2 diabetesAlternative NamesComplications of diabetesCauses, incidence, and risk factorsInsulin is a hormone made by the pancreas, an organ located behind the stomach. Insulin is needed to move glucose (blood sugar) into cells, where it is stored and later used for energy.Diabetes is caused by a problem in the way your body makes or uses insulin. There are several types of diabetes. This article discusses the possible complications related to diabetes.Signs and testsIf you have diabetes, you should see your health care provider every 3 months. At these visits you can expect the health care provider to:Check your blood pressureCheck the sensation (feeling) on your feetCheck the skin and bones of your feet and legsExamine the back part of your eyes with a lighted instrument called an ophthalmoscopeSupport GroupsFor additional information, see: Diabetes resources.ComplicationsAfter many years, diabetes can lead to serious problems throughout your body, including your eyes, kidneys, and nerves.EYE PROBLEMSDiabetes can also damage blood vessels in the eyes, causing vision problems or blindness. Conditions may include:CataractsDiabetic retinopathyGlaucomaMacular edemaFOOT AND SKIN PROBLEMSPeople with diabetes are more likely to have foot problems because of nerve and blood vessel damage. Small sores or breaks in the skin may turn into deep skin ulcers if not treated properly. If these skin ulcers do not improve, or become larger or go deeper, amputation of the affected limb may be needed. (See: Diabetes foot care.)HEART AND BLOOD VESSELSIf you have diabetes, your risk of a heart attack is the same as someone who has already had a heart attack. Both women and men with diabetes are at risk. You may not even have the typical signs of a heart attack. Other problem with the heart and blood vessels include:Damage to blood vessels that supply the legs and feet (peripheral vascular disease)High blood pressure (hypertension)High cholesterolStrokeNERVE PROBLEMSDiabetes can damage nerves, which means you may not feel an injury until a large sore or infection develops. Nerve damage causes pain and numbness in the feet, as well as a number of other problems with the stomach and intestines, heart, and other organs. (See: Diabetic neuropathy.)OTHER COMPLICATIONSInfections of the female genital tract, the skin, or the urinary tractKidney disease and kidney failure (diabetic nephropathy)Problems attaining or maintaining an erection (impotence)Calling your health care providerCall your health care provider if you have:Numbness, tingling, or pain in your feet or legsProblems with your eyesightSores or infections on your feetSymptoms of high blood sugar (being very thirsty, having blurry vision, having dry skin, feeling weak or tired, needing to urinate a lot)Symptoms of low blood sugar (weakness or tiredness, trembling, sweating, feeling irritable, unclear thinking, fast heartbeat, double or blurry vfision, feeling uneasy)PreventionYou should learn basic diabetes management skills. They will help prevent complications and the need for medical care. These skills include:How to handle sick daysHow to recognize and treat low and high blood sugarHow to take medications, if neededHow to test and record your blood sugar level (See: blood glucose monitoring.)What to eat and whenWhere to buy diabetes supplies and how to store themIt may take several months to learn the basic skills. Always continue to education yourself about the disease and its complications. Learn how to control and live with diabetes. Over time, stay current on new research and treatment. (See: Diabetes education.)The American Diabetes Assocation recommends keeping blood sugar levels in the range of:80 - 120 mg/dL before meals100 - 140 mg/dL at bedtimeEXERCISERegular exercise is important for everyone, but especially if you have diabetes. Regular aerobic exercise lowers blood sugar without medication and helps burn excess calories and fat so you can mange your weight.Exercise can help your overall health by improving blood flow and blood pressure. Exercise also improves your ability to handle stress.The following are important for preventing complications of diabetes:Get yearly tests to be sure your kidneys are working well (microalbuminuriaand serum creatinine)Have your blood pressure checked at least every year (pressure should bve 130/80 mm/Hg or lower)Have your cholesterol and triglyceride levels checked yearly (LDL levels should be 100 mg/dL or below)Have your glycosulated hemoglobin (HbA1c) check every 6 months if your diabetes is well controlled or every 3 months if it's notSee the dentist every 6 months for a thorough cleaning and exam. Make sure your dentist and hygienist know you have diabetesVisit your ophthalmologist at least once a year -- more often if you have signs of diabetic retinopathyFOOT CARETo prevent problems with your feet, you should:Check and care for your feet EVERY DAY, especially if you already have known nerve or blood vessel damage or current foot problems. Follow the instructions below.Get a foot exam by your health care provider at lesat twice a year and learn whether you have nerve damageImprove control of your blood sugarMake sure you are wearing the right kind of shoesStop smoking if you smoke(See: Diabetes foot care.)MEDICATIONS TO PREVENT COMPLICATIONSSince those with diabetes have a much higher chance of developing heart disease, kidney disease, and other medical problems, they may need to take certain medicines to treat or prevent these problems.An ACE inhibitor (or ARB) is often recommeded:As the first choice medicine for treating high blood pressureFor those who have signs of early kidney disesae (microalbuminuria)ACE inhibitors include captopril (Capoten), enalapril (Vasotec), quinapril (Accupril), benazaeprl (Lotensin), ramipril (Altace), perindopril (Aceon), and lisinopril (Prinivil, Zestril)Statin drugs are usually the first choice to treat an abnormal cholesterol level. Aim for LDL cholesterol level less than 100 mg/dL. (See: High cholesterol and triglycerides.)To prevent heart disease, aspirin is recommended most often for people with diabetes. Ask your doctor if aspirin is right for you.ReferencesAmerican Diabetes Association. Standards of medical care in diabetes -- 2009. Diabetes Care. 2009;32:S13-S61.Buchwald H, Estok R, Rahrbach K, et al. Weight and type 2 diabetes after bariatric surgery: systematic review and meta-analysis. Am J Med. 2009;122(3):248-256.e5. ReviewEisenbarth GS, Polonsky KS, Buse JB. Type 1 Diabetes Mellitus. In: Kronenberg HM, Melmed, S, Polonsky KS, Larsen PR, eds. Williams Textbook of Endocrinology. 11th ed. Philadelphia, Pa: Saunders Elsevier; 2008: chap 31.In the clinic. Type 2 diabetes. Ann Intern Med. 2007;146:ITC-1-15.U.S. Preventive Services Task Force. Screening for type 2 diabetes mellitus in adults: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med. 2008;148(11):846-54.