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Can a point mutation cause a change in one single nucleotide in a DNA sequence?
Yes, a point mutation can cause a change in one single nucleotide in a DNA sequence.
What happens if you change a single base in codon?
If one base in a codon was changed, this would be a point mutation. This may not cause any change in the structure of the protein, or it could be severely damaging. Since most amino acids have more than one codon, it's possible that the mutation would result in one of the other codons for that amino acid. In that case, there would be no change in the sequence of amino acids, and no change in the structure or function of the protein. A point mutation might also result in a codon that codes for a totally different amino acid, which can cause a genetic disorder. One example of a genetic disorder caused by a point mutation is sickle cell anemia. It's also possible that the point mutation could cause the codon to code for a stop signal. Please read the article in the related links for more information.
WHAT HAPPEN IF YOU CHANGE A SINGLE BASE CODON?
If one base in a codon was changed, this would be a point mutation. This may not cause any change in the structure of the protein, or it could be severely damaging. Since most amino acids have more than one codon, it's possible that the mutation would result in one of the other codons for that amino acid. In that case, there would be no change in the sequence of amino acids, and no change in the structure or function of the protein. A point mutation might also result in a codon that codes for a totally different amino acid, which can cause a genetic disorder. One example of a genetic disorder caused by a point mutation is sickle cell anemia. It's also possible that the point mutation could cause the codon to code for a stop signal. Please read the article in the related links for more information.
Which of the following is a point mutation that does not produce a frame shift?
A point mutation that does not produce a frame shift is when one single base is replaced by a different base. This changes the DNA sequence, but does not cause a frame shift because it is a switch not an addition or subtraction of a base.
What is a genetic mutation that does not result in a change in the amino acid sequence of the resulting protein?
It is neutral mutation. Codons are made up of 3 base pairs. This gives 64 different combinations, but there are only 20 amino acids, so some different codons will code for the same amino acid. When the base pair that is changed doesn't cause a change in the amino acid it codes for, then ultimately nothing happens
When would a mutation in DNA not cause a change in how the gene is expressed or in which proteins are made?
If a point mutation occurs in a location that is not critical to the structure and function of the protein, it will not change the way the gene is expressed. Also, since most amino acids have more than one codon, if the point mutation resulted in a codon for the same amino acid without the mutation, it will not change the way the gene is expressed.
What happens if only one amino acid is coded incorrectly?
If only one amino acid is coded incorrectly in a protein sequence, it may result in a missense mutation. This could potentially lead to a change in the structure and function of the protein. The impact of the mutation would depend on the specific amino acid involved and its location within the protein.
When a nitrogenous base is inserted or delete how does that affect the amino acid sequence?
The amino acid sequence is shifted, and this kind of mutation is called a frame shift mutation. All of the amino acid sequence after the mutation will be changed, which will cause a change in shape of the protein, which will then probably result in a nonfunctional protein, since the shape of a protein determines its function.
How a mutation in DNA many NOT necessarily have a bad affect on the gene's protein product?
The mutation may still code for the same amino acid, or it may cause a change in a non-critical region of the protein.
How many amino acids would this protein have if a mutation occurred and the 7th dna base pair of the dna strand was changed from a-t to t-a?
This mutation would cause a frameshift mutation, shifting the reading frame of the DNA sequence. Most likely, this would lead to a completely different protein being translated, resulting in a protein with a different sequence of amino acids from the original protein. The number of amino acids would depend on the specific changes in the protein sequence caused by the frameshift mutation.
Why does a deletion mutation usually cause more defects during protein synthesis than a point mutation?
Deletion mutations can affect the entire base sequence.
What is the difference between a point mutation and an insertion and deletion?
Because a point mutation is the replacement of a single base with another base. Thus, if the replacement base codes for the same type amino acid, such as a hydrophobic type amino acid replacing a hydrophobic amino acid, no change to the protein coded for will occur. If a deletion mutation occurs then the code for the protein is disrupted and the protein product is probably going to be useless to the body and may even cause a disease.
