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How can a single point mutation cause a change in the amino acid?
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∙ 12y ago
Be cuz he has a lumpy tummy.
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∙ 12y ago
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What happens if you change a single base in codon?
If one base in a codon was changed, this would be a point mutation. This may not cause any change in the structure of the protein, or it could be severely damaging. Since most amino acids have more than one codon, it's possible that the mutation would result in one of the other codons for that amino acid. In that case, there would be no change in the sequence of amino acids, and no change in the structure or function of the protein. A point mutation might also result in a codon that codes for a totally different amino acid, which can cause a genetic disorder. One example of a genetic disorder caused by a point mutation is sickle cell anemia. It's also possible that the point mutation could cause the codon to code for a stop signal. Please read the article in the related links for more information.
What happens if only one amino acid is coded incorrectly?
If an amino acid is coded incorrectly, then it would change the entire structure of the DNA and could possibly cause a mutation
WHAT HAPPEN IF YOU CHANGE A SINGLE BASE CODON?
If one base in a codon was changed, this would be a point mutation. This may not cause any change in the structure of the protein, or it could be severely damaging. Since most amino acids have more than one codon, it's possible that the mutation would result in one of the other codons for that amino acid. In that case, there would be no change in the sequence of amino acids, and no change in the structure or function of the protein. A point mutation might also result in a codon that codes for a totally different amino acid, which can cause a genetic disorder. One example of a genetic disorder caused by a point mutation is sickle cell anemia. It's also possible that the point mutation could cause the codon to code for a stop signal. Please read the article in the related links for more information.
When would a mutation in DNA not cause a change in how the gene is expressed or in which proteins are made?
If a point mutation occurs in a location that is not critical to the structure and function of the protein, it will not change the way the gene is expressed. Also, since most amino acids have more than one codon, if the point mutation resulted in a codon for the same amino acid without the mutation, it will not change the way the gene is expressed.
What is a genetic mutation that does not result in a change in the amino acid sequence of the resulting protein?
It is neutral mutation. Codons are made up of 3 base pairs. This gives 64 different combinations, but there are only 20 amino acids, so some different codons will code for the same amino acid. When the base pair that is changed doesn't cause a change in the amino acid it codes for, then ultimately nothing happens
When a nitrogenous base is inserted or delete how does that affect the amino acid sequence?
The amino acid sequence is shifted, and this kind of mutation is called a frame shift mutation. All of the amino acid sequence after the mutation will be changed, which will cause a change in shape of the protein, which will then probably result in a nonfunctional protein, since the shape of a protein determines its function.
How a mutation in DNA many NOT necessarily have a bad affect on the gene's protein product?
The mutation may still code for the same amino acid, or it may cause a change in a non-critical region of the protein.
How can a point mutation alter the final structure of a protein?
In a point mutation, one nitrogen base is substituted for the correct base. Since most amino acids can be coded for by more than one codon, there may be no consequence to this mutation. However, sometimes a point mutation results in an incorrect amino acid being added to the amino acid sequence of the protein. This can cause a change in the shape and therefore function of the protein, which can be a harmful mutation. Two genetic disorders caused by a point mutation are cystic fibrosis and sickle cell anemia.
What is the difference between a point mutation and an insertion and deletion?
Because a point mutation is the replacement of a single base with another base. Thus, if the replacement base codes for the same type amino acid, such as a hydrophobic type amino acid replacing a hydrophobic amino acid, no change to the protein coded for will occur. If a deletion mutation occurs then the code for the protein is disrupted and the protein product is probably going to be useless to the body and may even cause a disease.
Why does a deletion mutation usually cause more defects during protein synthesis than a point mutation?
Deletion mutations can affect the entire base sequence.
Write a sentence using silent mutation missense mutation frameshift mutation non sense mutation deletion dupication inversion transloction gene rearangement?
a silent mutation is one that doesn't affect the overall physiological role or roles of the species, so it has no change or noticeable change in the subject. A missense mutation simply causes one amino acid to change into a different amino acid, it could cause a problem or it could not. A frameshift is when an amino acid is removed. The removal moves all amino acids hereafter over one, which changes the codon sequence of the entire gene. This mutation can be detrimental. A nonsense mutation is usually classified as a premature stop codon. It's a point mutation that can cause a gene to become smaller than it really is. an inversion is the reversal of a gene, which is also very problematic. Translocations are removal of one amino acid, which is then transferred to a separate nonhomologous chromosome. A gene rearrangement is just another name for a duplication, inversion, or deletion. It's not one sentence, but it is a hell of a lot of good information. email for questions: bmalinak@gmail.com
Why does deletion mutation usually cause more defects protein synthesis than a point mutation?
A point mutation will change only one particular base of the codon, so it will only cause a change in one of the amino acids that will make up the protein. A deletion mutation will completely remove a base- causing a change in every amino acid that follows the deletion. Here is an example with a sentence, using three letter words (since amino acids are determined from 3 letter codons). THE FAT CAT ATE ONE RAT. A point mutation would change only one letter (like changing the C to a B). The new sentence is only slightly changed: THE FAT BAT ATE ONE RAT. A deletion mutation would remove a letter (like deleting the C). The new sentence will now be completely changed from the deletion on. THE FAT ATA TEO NER AT. See the difference??? Point mutations usually take place during DNA replication. A single point mutation can change the whole DNA sequence.
