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Acyclovir gets phosphorylated by the thymidine kinase of herpes. During this process, a base and sugar gets added to the drug. Acyclovir's OH group becomes a monophosphate so a triphosphate can be formed. It can enter the cell and affect it's DNA sequence by terminating its chain.
What else can I help you with?
How does acyclovir work as an anti-viral drug?
Acyclovir can help treat herpes. The herpes's simplex virus thymidine kinase can phosphorylate the drug into its monophosphate. As it is a poor substrate for the thymidine kinase of humans, it is not toxic for non-infected cells. This drug competes with dGTP as a competitive inhibitor. Once is enters the DNA, it can act as a chain terminator.
What is the terminator in mRNA synthesis?
The terminator in mRNA synthesis is a specific DNA sequence that signals the end of transcription. When the RNA polymerase reaches the terminator sequence, it stops transcribing the mRNA molecule, releasing it from the DNA template.
What is a DNA terminator sequence?
A DNA terminator sequence is a specific nucleotide sequence that signals the end of transcription for RNA polymerase, thus stopping the synthesis of RNA from DNA. It usually contains a stem-loop structure that causes RNA polymerase to dissociate from the DNA template.
Which process stop when rna polymerase comes to a terminator?
Transcription is the process that stops when RNA polymerase is terminated.
What signals the termination of translation?
Translation terminates when a stop codon (UAA, UAG, or UGA) is reached in the mRNA. This stop codon is recognized by release factors, which promote the release of the completed polypeptide chain from the ribosome.
Which process uses bacteria to copy DNA?
Polymerase chain reaction
Who discovred DNA?
florie and chain
What is an error in the DNA chain?
A mutation
Which type of enzyme ensures that the correct base for growing the chain is aligned with the template chain?
DNA polymerase is the enzyme responsible for ensuring that the correct base is aligned with the template chain during DNA replication. It has a proofreading function that helps in accurately replicating the DNA sequence.
What are chain - like carbon atoms are?
DNA
Molecules of DNA are composed of a long chain are called?
A DNA molecule is composed of long chains of DNA nucleotides.
Which is used to copy DNA for DNA fingerprinting?
PCR
