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There are a few reasons why a person should receive a blood transfusion, lets start off with the most common:

- Your hemoglobine(Hb) concentration is very low(around 5,5 mmol/L, differs from hospital), in other words, you have an anemia(You have an anemia when: for women at 7,5 mmol/L, men at 8,0mmol/L).

Receiving a blood transfusion will increase your hemoglobine concentration with approx. 1,5 mmol/L each erythrocyt unit(One bag of concentrated erythrocytes).

There are alot of causes for a low Hb, a few examples are:

iron deficiency, blood lost, auto-immune illness(Your own body is destroying its own erythrocytes) or low production of erythrocytes.

- Thallassemia, This is an disorder of your bone marrow. With this disorder your bone marrow is not able to create hemoglobine the right way. It is able to make erythrocytes, but no good ones. Your liver and milt filters of the blood and will detect these bad erythrocytes and destroy them. People with this disorder have to receive a blood transfusion monthly. The only cure is to receive a bone marrow donation.

- Your coagulation is drastically slow. You will not receive a normal bag of erythrocytes, but a bag of blood plasma. This plasma still contains the coagulation proteins(Factors, example: factor VII etc.). With these you will get your coagulation faster, else risks are you will have a high chance of bleedings.

- Your trombocytes are very low. You will receive a bag of concentrated trombocytes. You will receive these when your trombocytes are below 50 /fL(may varray per hospital).

This is a short answer to your question, other reasons may be added by other people.

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Q: How can blood transfusion help thalassemia patients?
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