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Early hypothyroidism is often asymptomatic and can have very mild symptoms. Subclinical hypothyroidism is a state of normal thyroid hormone levels, thyroxine (T4) and triiodothyronine (T3), with mild elevation of thyrotropin, thyroid-stimulating hormone (TSH). With higher TSH levels and low free T4 levels, symptoms become more readily apparent in clinical (or overt) hypothyroidism.

Hypothyroidism can be associated with the following symptoms:

Early
  • Poor muscle tone (muscle hypotonia)
  • Fatigue
  • Any form of menstrual irregularity and fertility problems
  • Hyperprolactinemia and galactorrhea
  • Elevated serum cholesterol
  • Cold intolerance, increased sensitivity to cold
  • Constipation
  • Rapid thoughts
  • Depression
  • Muscle cramps and joint pain
  • Thin, brittle fingernails
  • Coarse hair
  • Paleness
  • Decreased sweating
  • Dry, itchy skin
  • Weight gain and water retention[10][11][12]
  • Bradycardia (low heart rate - fewer than sixty beats per minute)
Late
  • Goiter
  • Slow speech and a hoarse, breaking voice - deepening of the voice can also be noticed, caused by Reinke's Edema.
  • Dry puffy skin, especially on the face
  • Thinning of the outer third of the eyebrows (sign of Hertoghe)
  • Abnormal menstrual cycles
  • Low basal body temperature
  • Thyroid-Related Depression
Uncommon
  • Impaired memory
  • Impaired cognitive function (brain fog) and inattentiveness.
  • A slow heart rate with ECG changes including low voltage signals. Diminished cardiac output and decreased contractility
  • Reactive (or post-prandial) hypoglycemia
  • Sluggish reflexes
  • Hair loss
  • Anemia caused by impaired haemoglobin synthesis (decreased EPO levels), impaired intestinal iron and folate absorption or B12 deficiency[16] from pernicious anemia
  • Difficulty swallowing
  • Shortness of breath with a shallow and slow respiratory pattern
  • Increased need for sleep
  • Irritability and mood instability
  • Yellowing of the skin due to impaired conversion of beta-carotene to vitamin A (carotoderma)
  • Impaired renal function with decreased glomerular filtration rate
  • Acute psychosis (myxedema madness) (a rare presentation of hypothyroidism)
  • Decreased libido in men due to impairment of testicular testosterone synthesis
  • Decreased sense of taste and smell (anosmia)
  • Puffy face, hands and feet (late, less common symptoms)
  • Gynecomastia
  • Deafness

(Source wikipedia)

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Q: How could hypothyroidism affect a patients general health?
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