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Early hypothyroidism is often asymptomatic and can have very mild symptoms. Subclinical hypothyroidism is a state of normal thyroid hormone levels, thyroxine (T4) and triiodothyronine (T3), with mild elevation of thyrotropin, thyroid-stimulating hormone (TSH). With higher TSH levels and low free T4 levels, symptoms become more readily apparent in clinical (or overt) hypothyroidism.
Hypothyroidism can be associated with the following symptoms:
Early- Poor muscle tone (muscle hypotonia)
- Fatigue
- Any form of menstrual irregularity and fertility problems
- Hyperprolactinemia and galactorrhea
- Elevated serum cholesterol
- Cold intolerance, increased sensitivity to cold
- Constipation
- Rapid thoughts
- Depression
- Muscle cramps and joint pain
- Thin, brittle fingernails
- Coarse hair
- Paleness
- Decreased sweating
- Dry, itchy skin
- Weight gain and water retention[10][11][12]
- Bradycardia (low heart rate - fewer than sixty beats per minute)
- Goiter
- Slow speech and a hoarse, breaking voice - deepening of the voice can also be noticed, caused by Reinke's Edema.
- Dry puffy skin, especially on the face
- Thinning of the outer third of the eyebrows (sign of Hertoghe)
- Abnormal menstrual cycles
- Low basal body temperature
- Thyroid-Related Depression
- Impaired memory
- Impaired cognitive function (brain fog) and inattentiveness.
- A slow heart rate with ECG changes including low voltage signals. Diminished cardiac output and decreased contractility
- Reactive (or post-prandial) hypoglycemia
- Sluggish reflexes
- Hair loss
- Anemia caused by impaired haemoglobin synthesis (decreased EPO levels), impaired intestinal iron and folate absorption or B12 deficiency[16] from pernicious anemia
- Difficulty swallowing
- Shortness of breath with a shallow and slow respiratory pattern
- Increased need for sleep
- Irritability and mood instability
- Yellowing of the skin due to impaired conversion of beta-carotene to vitamin A (carotoderma)
- Impaired renal function with decreased glomerular filtration rate
- Acute psychosis (myxedema madness) (a rare presentation of hypothyroidism)
- Decreased libido in men due to impairment of testicular testosterone synthesis
- Decreased sense of taste and smell (anosmia)
- Puffy face, hands and feet (late, less common symptoms)
- Gynecomastia
- Deafness
(Source wikipedia)
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