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Louis Pasteur used the common sense for the vaccine production. He infected the rabbits with rabies virus. When the rabbit developed the rabies and died of rabies. He removed the brains of rabbits and dried them, for about ten day, after making small pieces of the same. This way he attenuated the rabies virus. Form this tissue he made the rabies vaccine. This was very crude vaccine and protection rate was about 60 % only. 18 people died of rabies, due to rabies vaccine in initial days of rabies vaccine production.

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11y ago

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