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The Great Plains is the huge expanse of flatlands from the Rocky Mountains eastward to the Mississippi River. The area also may be referred to as the American Plains.
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Great American desert.
George Rogers Clark
Some American physical features include the Appalachian Mountains, the Great Lakes, the Mississippi River, the Great Plains, the Rocky Mountains, and the Great Basin Desert.
The North American Plains which stretch from the Mississippi River to the Rocky Mountains and from the Hudson Bay to the Gulf of Mexico
The early settlers called the grasslands between the Mississippi River and the Rocky Mountains the "Great Plains" because of the vast flat expanses of grassland that characterized the region.