Inhibit the movement of ionic calcium across the cell membrane. This reduces the force of contraction of heart muscles and arteries.
Nimodipine is in a group of drugs called calcium channel blockers. Nimodipine relaxes (widens) blood vessels and improves blood flow by blocking cacium absoption.
There are many chemical drugs which are natural calcium channel blockers. Some include Diltiazem, Amlodipine, Verapimil, and Nifedipine. Many more are available however some are not allowed for sale in the USA.
No, calcium channel blockers work at the level of muscle cells.
Calcium channel blockers block the entry of calcium into muscle cells in artery walls. Muscle cells need calcium to constrict, so reducing their calcium keeps them more relaxed and lowers blood pressure.
Neuromuscular blocking agents are medications that work by blocking the transmission of nerve signals to the muscles, resulting in muscle paralysis. They are used during surgical procedures to facilitate intubation, reduce muscle movements, and provide muscle relaxation. These medications are administered by anesthesiologists and require monitoring to prevent complications.
The patient taking calcium channel blockers should keep taking the medicine, to give it time to work. Once it begins to work and symptoms improve, it should continue to be taken as prescribed.
Taking calcium channel blockers with certain other drugs may affect the way the drugs work or may increase the chance of side effects.
Ziac is not a calcium channel blocker; it is a combination medication that contains bisoprolol, a beta-blocker, and hydrochlorothiazide, a thiazide diuretic. It is primarily used to treat high blood pressure. While calcium channel blockers also help manage hypertension, they work through a different mechanism compared to the components of Ziac.
Yes, local anesthetic agents are weak bases, not weak acids. They work by blocking sodium channels in nerves, preventing the conduction of pain signals.
It depends on the channel/transporter being blocked. For example, it's well established that a type of diuretic called a loop diuretic (eg, furosemide) causes hypercalciuria, a fancy term for excess calcium in the urine. Loop diuretics work by blocking a sodium-potassium-chloride transporter in the kidney, and indirectly result in decreased calcium reabsorption from the urine. Because most kidney stones are made of calcium, the excess urinary calcium caused by loop diuretics can predispose people to kidney stones. By contrast, thiazide diuretics (eg, hydrochlorothiazide) commonly used to treat high blood pressure often cause hypocalciuria, which is decreased urinary calcium. Thiazides work by blocking a sodium-chloride transporter in the kidney, indirectly causing increased calcium reabsorption so less ends up in the urine. So thiazide is a reasonable medication to use for treating high blood pressure in patients prone to kidney stones. Thiazide and loop diuretics aren't technically "channel blockers", but I'm assuming you're using the term loosely. Perhaps I'm wrong though.
No, the ability of first strike does not work when a creature is blocking.
Local anesthetics like lidocaine can be used to anesthetize the tongue, reducing taste sensations. These agents work by blocking the transmission of signals from the taste buds to the brain, temporarily numbing the area.