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Many of the changes in metabolism during exercise have effects throughout the body. In muscle, there is a increase in blood flow caused by both local factors as well increases in circulating adrenaline. These same hormones also increase the release of glucose into the blood by increasing the break down of glycogen stores. Glucose enters the muscle by because the concentration of glucose outside of the muscle cells is much greater than within (where glucose is being metabolized to make ATP). Oxygen is increased by increases in the rate of respiration and taking deeper breaths. Nonetheless strenuous exercise in muscle results in an energy and oxygen deficit that will lead to the exhaustion of the supply of ATP needed for continued muscle activity.

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Q: How do muscles continue to function during exercise as need for oxygen and glucose is increased?
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