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Stromal Fibroblasts produce the connective tissue that surrounds tumor cells. As cancer grows it demands more nutrients so more and more of these stromal cells sacrifice themselves to provide recycled nutrients to tumor cells. Without recycled nutrients provided by fibroblasts, tumor cells are more fragile and die. Researchers propose that available drugs (now on the market), which sever the "parasitic" connection between tumor cells and fibroblasts, may be effective therapeutics.
What else can I help you with?
Can Gastrointestinal stromal tumor metastic in the brain?
yes
What is the first step that leads to development of a tumor?
a mutation occurs in a cell then a tumor forms
Is a Wilms tumor infectious or noninfectious?
Wilms tumor is a cancerous tumor (noninfectious). It is a leading cause of cancer in young children, affecting the kidney and its development.
What has the author Michael Kasper written?
Michael Kasper has written: 'Cytokeratins in intracranial and intraspinal tissues' -- subject(s): Adenoma, Analysis, Central nervous system, Chemistry, Epithelium, Fibroblasts, Keratin, Neurochemistry, Tumor proteins
Should someone with a brain tumor drive?
Whether a person with a brain tumor can drive depends on whether they have seizures or memory issues and what drugs they are taking to manage the symptoms. Their doctor or a family member is probably close enough to make sure they do not drive when it is not appropriate.
How are tumors managed in pediatric cases?
Wilm's tumor (nephroblastoma) is a tumor in the kidneys that forms during embryonic development. The tumor is due to a genetic abnormality; and approximately 80% of children are diagnosed between one and five years of age.
what is the meaning of Melanoma?
(a) A tumor containing dark pigment. (b) Development of dark-pigmented tumors.
What is the function of a tumor suppressor gene in the human body?
Tumor suppressor genes help regulate cell growth and prevent the development of cancer by controlling cell division and repairing damaged DNA.
What is the difference from a hard tumor or a soft tumor?
A hard tumor is not a tumor
How does the presence of lactic acid in the tumor microenvironment contribute to the progression and development of cancer?
The presence of lactic acid in the tumor microenvironment can contribute to the progression and development of cancer by promoting tumor growth, invasion, and resistance to treatment. Lactic acid can create an acidic environment that helps cancer cells survive and thrive, as well as promote the formation of new blood vessels to supply nutrients to the tumor. Additionally, lactic acid can suppress the immune system's ability to attack cancer cells, making it harder for the body to fight off the disease.
How do tumor suppressor genes work to prevent the development of cancer?
Tumor suppressor genes help prevent cancer by regulating cell growth and division. They can repair damaged DNA, trigger cell death, or stop cells from dividing uncontrollably. When these genes are mutated or inactive, cells can grow out of control, leading to the development of cancer.
What is the abnormal development or growth of cells?
The abnormal development or growth of cells is called tumor or neoplasm, which can be benign or malignant. In the case of cancer, the cells divide uncontrollably and can invade surrounding tissues.
