Como son tus padres
"¿Cómo están tus padres?" translates to "How are your parents?"
It means: how are your parents
"They are your parents."
how are the girls -- How are they (all boys or a mixture of girls and boys)?
Those of your parents are your grandparents.
What are your cousins like? literally, "how are your cousins."
De donde son tus padres?
¿De dónde son tus padres? is asking "Where are your parents from?" The proper answer is "My parents are from _____" (Mis padres son de _______)
Tus ojos brillan como el sol. "You eyes shine like the sun." Or "Tus ojos son como la luz del sol."
"¿Qué cosas hacen tus padres?" translates to "What things do your parents do?"
Tus ojos y cara son hermosas.
cómo son tus amigos/as means how are your friends The answer means physically (tall) or in terms of personality (funny), not in terms of health. (That would use the verb estar instead.)