How do you discover the new multiple antibiotics and how to use them?

Answer 1

Due to large scale misuse of antibiotics by the unqualified doctors, you have landed in the problem of emergence of multi drug resistant bacteria. Now you have to invent the new antibiotics. Most of the best antibiotics are probably already discovered. Here is the way by which you will be able to find the new group of antibiotics to treat the infections with multi drug resistant bacteria. As you know you have most of the antibiotics that has derived from the Fungi. There are very few antibiotics that are derived from the bacteria. Bacitracin, Polymixin B, Amphotericin B are derived from the bacteria. They are much more toxic as compared to the antibiotics that are derived from Fungi. The antibiotics that will be derived from the bacteria will be toxic as well. But they are easy to discover and should be made available for the infections due to multi drug resistant bacteria. As you know that most of the bacterial infections are due to single type of bacteria. You usually get the respiratory tract infection due to single type of bacteria, for example. This usually happens when your immunity has lowered down due to respiratory viral infections. The simple question arise that as to why the multiple type of bacteria do not take over to cause the infection. The reason is as simple as Sir Alexander Fleming thought about the growth of penicillin. The given bacteria secretes the chemical to inhibit the growth of other bacteria. You may have to identify the different chemicals that are secreted by the bacteria. This chemical when added to the culture of other bacteria will inhibit the growth of those other bacteria. This why you can identify the large number of antibiotics that can inhibit the growth of other bacteria. Now the question arise as to how to use these antibiotics. Say for example the antibiotic produced by Mycoplasma pneumoniae can not be used against the same organism. It can be used against the other organisms. So you will have to go for the culture and sensitivity of the organism before you go for the treatment of the systemic bacterial infections. The above article is submitted to the science community for expert opinion and necessary action.