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The lymph nodes store and make B cells which fight antigens (foreign substances in the body).

To elaborate on and attempt to complete the answer, the lymph nodes are where the adaptive immune response begins and is maintained (contrasted with the innate immune response). Dendritic cells circulate throughout the body and pick up antigens (foreign substances in the body, e.g., those of microorganisms such as bacterial cell wall proteoglycans) associated with infected tissue and upon returning to the lymph nodes present them to T and B lymphocytes that pass through or may even reside at the node. The lymphocytes that now recognize the particular antigen proliferate and return to the main circulation and attack the associated microorganism. The adaptive immune response, as by proliferation of antigen specific lymphocytes, is also maintained at the lymph nodes after the infection is gone in case reinfection by the same microorganism occurs.

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13y ago
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Lymph nodes produce lymph, which filters waste and bacteria so they do not enter the bloodstream. When the presence of a foreign substance is recognized, they produce T-cell and B-cell lymphocytes, which go to the infected area to destroy the invader.

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Q: What is the main role of lymph nodes in the bodys defence?
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