You don't, dummie. Have you even played a Pokemon game before? Misty is only in the Kanto region. She is Cerulean City's Gym Leader, and only travels with you in the anime. You will never find her, period. Go out and learn something.
She's at the end of route 25
at the end of the cerulean cape (route 25)
Misty is located around Bill's House at the Cerulean Cape, but you won't find her until you finish solving the problem at the Power Plant.
misty will be a gym leader in HeartGold and SoulSilver
After you defeat Misty, You can go catch suicune by Bill`s house.
Misty is at the Cerulean Cape. It's close to Cerulean City.
Misty has a 49 Golduck 49 Quasire 52 lapras and 54 starmie
you can find misty at the end of route 25 but also there are 8 trainers u have to go through and when you do just go past that house and misty should be there on a date
route 25
you need to get the kanto power plant and talk to the manager then you go to misty's gym and find a team rocket grunt you follow him and beat him then you find the machine part and return it to the power plant then go to bill's house then go up the hill next to it then you see misty
top of rout rout 25 =]
it is the place where th gym leader is Misty