Buy the PlayStation 3 version of the game, it only requires one (1) Blu-Ray disc. You can also buy a digital copy of the game from the PlayStation Store which doesn't require any discs, but does require 12 gigabytes of hard drive space. Another option is to buy the digital version of the game on Windows, such as off Steam. No discs, but it will require a large amount of hard drive space.
Yes.
Well maybe its because the game came in a two disc set... -_-
Normally not but you can install a app where you can play it without disc.
Read my answer under the question How do you play a PC game without the disc in the disc drive? on this site.
No you need the disc to play it.
Yes just buy the download otherwise the console needs the disc to play the game
yes
Mass Effect and Mass Effect 2 are both single player. There are no multiplayer modes
Can the PC play the Xbox 360 game Disc. No of course not. They are not the same game and only have the same title. You don't even have the same title and want to save a different game in the series on a platform it will not play on
Yes i can play.
It is possible. You have to download a crack, which makes it possible to play the game without a disc. But this is illegal.
yes you can play the game without the disc