Jesús es mi mejor amigo
Por mi amigo mejor. - By my best friend.
You could say "mejor amigo/a".
Mis mejores amigos would be the best way to say "my best friends" in Spanish.
Best of luck to you my friend is very easy to translate. Best of luck to you my friend = mejor de las suertes a mi amigo
Soy tu mejor amiga.
perdí a mi mejor amigo
If it is a male best friend, you say, "mejor amigo, a."
To say hello friend in Spanish you can say "hola amigo".
I think she would say that Jesus Christ was her best friend, even at times she felt he had abandoned her.
Quien es tu mejor amigo(a) ---- as an affirmation, not a question
my friend = mi amigo
Jesus in Spanish is "Jesús". No disrespect is intended to Jesus Christ or our Spanish speakers but to English speakers Jesus sounds like you are saying "Hey Seuss".