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It depends on the sense in which you mean it.

If it is in a normal conversation where someone says, "Maybe it's just me, but I wouldn't do 'x". Does that make me crazy?", the response would be, "No, no estás loco."

If it is a situation where you are talking to a person who has been locked in a mental institution and has serious doubts about his sanity, the response would be, "No, no eres loco."

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9y ago

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